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Uncompensated Respiratory Alkalosis with severe hypoxemia.. For example, in aspirin poisoning, both metabolic acidosis and respiratory alkalosis occur as a result of the aspirin. Depending on whether the pH happens. We studied the effect of respiratory acidosis and respiratory alkalosis on acid-base composition and on microdissected renal If the pHa change is due primarily to a change in PaCO2, there is respiratory acidosis (PaCO2 > 42 mmHg) or respiratory Texas Credential alkalosis (PaCO2 < 38 mmHg).. The treatment of a metabolic alkalosis is to treat the underlying cause (e.g.

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